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Random Gleanings

TAGline • 1994
Vaccine Victory (Of Sorts), Or “Yes, Only Not In My Backyard.” — Genentech’s Don Francis Has the Last Word. WHO gave the green light to vaccine prevention studies in developing countries with the very products judged by US officials to be unlikely to confer protection. Southeast Asia and South America are lining up as the…

Shift Rift: Series of Research Papers Take To Task Would-Be Discoverers Of Cytokine Switch

TAGline • 1994
Series of Research Papers Take To Task Would-Be Discoverers Of Cytokine Switch Scrutinizing the Knock-out Mice It was the big story out of Amsterdam, summer of 1992. Later that fall at the Vth International Vaccine Cooperative meeting in Chantilly, VA, it gave birth to Jonas Salk’s highly publicized “Reconceptualization of the Basic Immune Correlates Required…

Not So Fast! With Its First Protease Trial Completed, Roche Races to FDA With Lukewarm Results, While Activists Cry ‘Foul’

TAGline • 1994
With Its First Protease Trial Completed, Roche Races to FDA With Lukewarm Results, While Activists Cry ‘Foul’ “Tarted-Up Anecdotes” Results from ACTG 229, a randomized, 24-week, 302-patient study comparing AZT+ddC+saquinavir (Ro 31-8959, Roche’s first protease inhibitor) vs. AZT+saquinavir vs. AZT+ddC, were released on May 31. The analysis was written up by Roland Bassett, David Schoenfeld…

Basic Research on HIV Infection: A Report From the Front

Publication • 1993
June 1993 Prepared by Gregg Gonsalves From the Introduction For over five years now, AIDS activists have focused their energies on clinical research and the drug development process, hoping to speed promising therapies for HIV infection to the people who need them. We have watched as AZT and then its cousins, ddI and ddC, have…

Pathogenesis + Activism, Speech by Mark Harrington

Publication • 1992
Speech by Mark Harrington Presented at VIII International Conference on AIDS, Amsterdam, July 22, 1992 I would like to dedicate my remarks today to my colleagues in the struggle against AIDS who did not survive the year since this group last met in Florence – to Charles Barber, Daniel Sotomayor, David Byar, David Lopez, Donald…

AIDS Research at the NIH: A Critical Review Part I: Summary

Publication • 1992
By Gregg Gonsalves and Mark Harrington VIII International Conference on AIDS, Amsterdam, the Netherlands, July 20, 1992 From the Introduction Since 1987, the activist critique of AIDS research has worked its way back: from drug approval at the regulatory level of the US Food + Drug Administration (FDA), to expanded access for drugs still under…
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