Tracking Down the Elusive CD8 Cell Factor In two separate reports, one in Science and one in Nature, researchers at the Paul Erlich Institute in Langen, Germany and at Dr. Robert Gallo's new lab at the University of Maryland announced…
35th Interscience Conference Unveils Results from Several Important Clinical Studies Protease and Paradox Early last month, TAG members Spencer Cox, Mark Harrington, Tim Horn and Michael Marco headed home after attending the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy…
AIDS Treatment Activists from Across the Land Gather to Share Expertise and Ideas "A conversation long overdue" TAG was the proud co-sponsor of the first national gathering of AIDS treatment activists, the National AIDS Treatment Advocates' Forum (NATAF), in Los…
FDA Antiviral Drugs Advisory Committee met earlier this month (November 6-8, 1995) to review approval applications for Roche's protease inhibitor saquinavir (trade name Invirase ), Glaxo-Wellcome's 3TC (lamivudine, trade name Epivir ) and Bristol's d4T (stavudine, trade name Zerit ).…
Community Envoy to Food and Drug Panel Urges Caution in Approving New Anti-HIV Therapueutics and in Providing Early Access "Badgering, hijacking activists" The FDA recently convened hearings regarding its Accelerated Approval program and the future use of changes in plasma…
Despite Pressure to Crown Combo King, 175 Investigators Soft-Pedal Combination Nucleoside Study's Startling Findings The Didanosine Surprise Even skeptics can find something to enjoy in the surprising results of AIDS Clinical Trials Group (ACTG) protocol #175. Last month's TAGline ("Combo…
In September, the Senate Appropriations Committee voted to maintain a consolidated appropriation for NIH AIDS research, sparing the Office of AIDS Research from becoming a paper tiger at the start of the next fiscal year. The Senate Committee's actions, however,…
ACTG 175 confirms the benefit of antiretroviral therapy in persons starting between 200-500 CD4 cells and before the development of AIDS (cf. ACTG 016, 109). ACTG 175 shows for the first time that initiating antiretroviral therapy at this time (CD4…
House Republican Plan Calls for AIDS Research Dollars to Be Mixed Into Pot For All to Avail Themselves Of The OAR as paper tiger In 1993, dozens of AIDS organizations and hundreds of AIDS researchers joined together to push for…
Controversial Nucleoside Study Awakens To A World Strangely Disaffected By Its Prepackaged Proclamation Beware the Composite Endpoint "Endlessly scrutinizing mediocrity" is how the 3,000 patient combination-versus- monotherapy mega-trial ACTG 175 was characterized in a July 29, 1991 issue of ACT…