December 1, 2025
Since January 2025, the U.S. government has frozen global HIV and tuberculosis (TB) research, prevention, and treatment programs. Here at home, research grants have been frozen or cut, public servants fired, and prevention, treatment, and public health programs gutted. Everything TAG and our communities have worked to build over the past four decades, in response to the HIV pandemic and the related ones of TB and hepatitis C virus (HCV), is being attacked and threatened with destruction.
If these cuts are allowed to stand, scientists estimate that millions of new HIV, TB, and HCV infections will occur, and much unnecessary suffering and death will take place.

TAG Staff and Board members hitting the streets of DC to protest disastrous cuts to PEPFAR and HIV funding.
All year long, TAG has been fighting back, raising the alarm with our partners and working to keep essential research from collapsing. We stand with allies everywhere to insist that research and programs to end these epidemics continues.
TAG acts quickly, independently, and in solidarity with the people whose lives are most vulnerable. We are trusted to speak truth to power, and 2025 has proven why that trust matters.

TAG’s TB Team at a March 2025 workshop in Hanoi, Vietnam, supporting the adoption of WHO’s latest TB policies on diagnostics, prevention, treatment, and nutrition to strengthen TB care across the region.
This work is personal to everyone at TAG. I myself was living with HIV when I co-founded TAG in 1992, and my life has been saved and lengthened thanks to the combination HIV therapies that our own work helped to accelerate and make possible. When this breakthrough arrived, TAG was among the first to push for global access to these treatments — reaching more than 20 million people with HIV, all now threatened by cruel budget cuts. We have seen far too many lives lost to preventable, treatable, and often curable diseases, and we know what happens when science is ignored.
We have also seen what becomes possible when determined people mobilize together for truth, equity, and justice. Our work has helped accelerate prevention, treatment, and cure efforts worldwide. Millions of lives have been extended and saved because of this shared commitment. With your partnership and generous support, we will continue fighting for the science that saves lives — every life.
We couldn’t do this work without you. Thank you, from all of us at TAG.
A luta continua!

Mark Harrington
Executive Director
mark.harrington@treatmentactiongroup.org
If you need more encouragement to give, take a look at “Inside the Fight: A Day in the Life of TAG’s TB Team.”

The crowd at 2025 CROI, demanding that science translate into action — equitable access, accountability, and real progress against HIV. TAG’s data-driven science was on full display and shared by numerous presenters.




