Gladstone Immunologist Challenges Thymic Status Quo, Teasing the Research Forward 'Problem of production' In HIV infection, the role of the thymus remains both hotly disputed and poorly understood -- whether its role in leading to the clinical manifestations of disease…
HIV Antibody Breakthrough in Transgenic Mice Could Prove Boon to Vaccine Effort Formaldehyde frozen fusion Recombinant HIV envelope vaccines to date have demonstrated the ability to elicit neutralizing antibodies to HIV strains from which they were constructed (as well as…
As Treatment Euphoria Ebbs, Stubborn Uncertainties Resurface But Are Unlikely to Be Resolved 'Unacceptable collective evasion' Paul Joseph Corser 1961-1999 Rod Sorge 1969-1999 With the prolonged demise of HIV eradication hypotheses and the growing appreciation of the various unpleasant realities…
Thymic Rebound, Naïve CD4+ T-Cell Repopulation Demonstrated in Individuals on HAART Vive le thymus! Even the most cutting edge immunology postdoc would have had his or her hands full preparing lesson plans from this month's "Frontiers of Immunology" piece, exhaustively…
AZT Monotherapy Veteran Checks out Chemotherapeutic Quitsville and Lives to Tell About It Don't try this at home In a recent highly unscientific and egregiously self-selective poll of HAART-experienced individuals (N=15) in New York City (most of them aging activists),…
AIDSVax Field Trial Makes a Splash While Humble Canarypox Phase II Plods Along Uncelebrated AIDS 'end game' While precious little has changed on the HIV vaccine front since last summer, when California-based VaxGen received the go-ahead to proceed with a…
At the Keystone HIV Pathogenesis symposium in January 1999, the Aaron Diamond AIDS Research Center's Douglas F. Nixon presented a paper entitled "Temporary Containment of Viral Replication After Cessation of Antiretroviral Drug Therapy." He reported on 4 individuals from one…
High-Technology Betrays Its Dark Side As Researchers and Patients Struggle to Interpret the Noise 'AIDS is back' When queried about his take on the Chicago retrovirus meeting and the state of HIV clinical care at large, a relatively high-profile-if arriviste-Floridian…
Scottish Scribe Tells of Resistance Testing Success, Superinfection, Flaws in Dual Protease Regimens 'Extensively reprised' In contrast to U.K. Drug Therapy Congresses past, where physician attendance from the U.S. was rife but that of U.S. activists lackluster, this year's late…
Tidy Clinical Science Stares Down Quotidien Chaos Theory; Might Not 'Late, Hard' Be Better After All? 'Irrelevant HAART' As part of an afternoon Glasgow plenary session entitled "Key Issues in Treatment Failure" (Wednesday 11 November 1998, 4th International Congress on…