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Welcome to the 2025 Pipeline Report. Our annual review provides an overview of research and development of innovations for diagnosing, preventing, treating, and curing HIV, hepatitis C virus (HCV), and tuberculosis (TB).

All these updates are downloadable PDFs, and we’ll be adding more soon, so please check back. Please feel free to use and share these widely in your scientific, policy, and advocacy work.

HCV

Long-Acting Therapies Trials Tracker for Hepatitis C, Opioid Use and Overdose Prevention Therapy, and Malaria
By By Joelle Dountio Ofimboudem, edited by Mark Harrington
November 2025

HIV

Antiretroviral Therapy
By Richard Jefferys
August 2025
HIV Vaccines and Passive Immunization
By Richard Jefferys
August 2025
PrEP and Microbicides
By Richard Jefferys
August 2025

TB

Tuberculosis Diagnostics
By Tejaswini Dharmapuri Vachaspathi
November 2025
Tuberculosis Treatment
By Lindsay McKenna
August 2025
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