Abbott, Trimeris/Roche Pricing Decisions Rekindle Old R&D Cost Questions Drug R&D Estimate (Millions) Source Invirase <$100 Interviews Norvir <$100 J. Leonard Crixivan $312* Internal memos Viracept $150 SEC docs. Agenerase <$200 SEC docs. * Goozner's estimate of Merck's total investment…
Little-Noticed Ban of Little-Used Drug Triggers Little-Known Investigation By Dr. Paul C. Bellman Whither the Checks and Balances? On April 9th, a New York City treating physician, Dr. Paul C. Bellman, submitted a treatise-length letter of protest to members of…
Vicissitudes of Medicine and Marketing Take Toll on Me-Too Line Up By Rob Camp B-I the New Salvage Outfit? Pipelines are almost as delicate and fragile as the ecosystems they go trampling through, writes TAG's Antiviral Project Director Rob Camp…
Bungled T-20 Launch Claims Its First Casualties, as Losses Spread By Mike Barr The Year of Fuzeon: Trimeris Daily Share Price -- Launch to Lability Source: Wall Street Journal Curse of the "Early Terminator" This month marks the one-year anniversary…
By Rob Camp Last year's pipeline report was warm, starry eyed and exuberant. How wrong can one guy be? Blow 1: The close of the year 2003 saw the "on-hold"-ing of SCH-C, the entry inhibitor that was moribund before the…
Against the Odds, Immune-Based Therapies for HIV Slog Along By Richard Jefferys Industry "Leery" Despite more than two decades of research, there is as yet no approved immune-based therapy (IBT) for HIV infection. And while antiretrovirals continue to course through…
By Richard Stern 12 December, 2003 Dear Friends: In response to my letter regarding the Toronto International AIDS conference, now scheduled for 2006, I have received the following letter from a person living with HIV/AIDS (PLWA) in Jamaica who wishes…
Activists Interrupt Vice Minister of Health at Inauguration Ceremony "We are not here to celebrate World AIDS Day. We are here because this is a day of mourning for us. Our friends continue to die because our government will not…
Activist Meeting With FDA Drugs Division Sets Broad Agenda for Change By Rob Camp Counting Our Blessings The night before the FDA meeting on 14 November 2003, twenty-five of your favorite activists at-large were putting together the game plan of…
Pointers and Prerogatives From and for the Unrepentant Problem Patient By Carlton Hogan Remembering Carlton "AIDS, when you come right down to it, is about loss. Health, life, mobility, financial security, independence, appearance, dreams: Virtually everything is eventually taken away…