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Reported maximum average reductions in plasma RNA with selected protease inhibitor combinations (in treament naive/experienced* individuals)
SQV .6 log S. Vella
SQV(new formulation) 1.5 log Roche
RTV 1.2-1.9 log Abbott
IDV 1.2-2.0 log Merck
NFV 1.5 log Markowitz
SQV+AZT 1.0 log S. Vella
SQV+ddC .6 log Roche NV*
SQV+AZT+ddC .8 log ACTG 229*
RTV+AZT 1.2 log Abbott
RTV+AZT+ddC 2.0-2.5 log Leibowich
IDV+AZT 1.4-1.5 log Merck
IDV+AZT+ddl 2.9 log Merck
IDV+AZT3TC >2.0 log Merck 035*
NFV+d4T 2.4-2.6 log Chapman

 

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