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2003 Antiretrovirals Pipeline Report

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By Rob Camp

The pipeline is bursting, with at least the following compounds twinkling in the eyes of scientists around the globe. It is by no means a full list, but those substances in red were presented at the recent CROI in Boston. There seems to be no lack of investigation — bench scientists are having a field day!

The following review is primarily from the 10th Retrovirus Conference in Boston. There is some earlier data from Barcelona XIV World AIDS Conference (July 2002) and data from the 4th Clinical Pharmacology meeting in Cannes (April 2003) as well. As organizing principle, I use the viral life cycle, i.e., where the drug acts, to organize this report.