July 2014 By Tim Horn and Simon Collins Introduction By 2024, antiretroviral treatment (ART) could be as different from that used today as triple therapy in 1997 was from AZT monotherapy in 1987, or as dramatically evolved as the once-daily…
July 2015 By Richard Jefferys Introduction The rise to prominence of cure research has continued over the past year, with every major scientific conference on HIV now featuring sessions and presentations on the topic. The U.S. National Institute of Allergy…
July 2015 By Tim Horn and Richard Jefferys Though global HIV incidence has declined by an estimated 33% since 2001, more than 2 million people continue to be infected with the virus every year – approximately 6,000 new infections every…
July 2015 By Polly Clayden Introduction The big news since the 2014 Pipeline Report is that there is finally a solid form of lopinavir/ritonavir (LPV/r) suitable for infants and young children. On 21 May 2015, the United States Food and…
July 2015 By Polly Clayden The most striking news since the 2014 Pipeline Report is from the START (Strategic Timing of AntiRetroviral Treatment) study.1 We now have evidence from a large, randomized, controlled trial to show that CD4 count is…
July 2015 By Simon Collins and Tim Horn INTRODUCTION As a global community of people living with HIV, our needs from the antiretroviral (ARV) pipeline have changed considerably over the last 20 years. Antiretroviral treatment (ART), particularly for people starting treatment,…
July 15, 2016 By Richard Jefferys INTRODUCTION The pursuit of a cure for HIV infection has become a central plank of the overall research portfolio, and this has been officially underpinned by the revised HIV/AIDS priorities announced by the U.S…
July 15, 2016 By Tim Horn and Richard Jefferys With the continued rollout and implementation of global, national, and regional HIV incidence targets and timelines, one thing has become abundantly clear: reducing HIV rates below endemic and epidemic levels in…
July 15, 2016 By Polly Clayden INTRODUCTION The development of new antiretroviral drugs and appropriate formulations for children continues to be far too slow. There are now 2.6 million children in need of antiretroviral treatment (ART) globally. Of those treated,…
July 15, 2016 By Tim Horn and Simon Collins INTRODUCTION The year 2016 marks 20 years since combination-based antiretroviral therapy (ART) first demonstrated durable, effective and sustained HIV control. An unprecedented period of drug discovery followed, and advances in viral…