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2013 EASL Update

  • Chad Cipiti

Streamlining HCV Treatment By Tracy Swan Treatment for hepatitis C virus (HCV) is becoming simpler, shorter, and more effective. All-oral combinations of direct-acting antivirals (DAAs) have pushed cure rates in HCV genotype 1 to over 90 percent. Still, we are…

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Hepatitis C Drug Development Catapults Onward

  • Chad Cipiti

June 2013 By Tracy Swan Thanks to Jules Levin The pace of, and progress in, hepatitis C virus (HCV) drug development are astonishing. In April 2011, proof-of-concept for safe, effective, peginterferon-free HCV treatment was announced. Since then, numerous trials have…

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Retrofitting for Purpose: Treatment Optimization

  • Chad Cipiti

June 2013 By Polly Clayden Last year’s Pipeline Report saw the addition of a new chapter exploring research into antiretroviral treatment optimization. This strategy includes the optimization of approved compounds, and possible future opportunities with those in late-stage development. This…

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The Pediatric Antiretroviral Pipeline

  • Chad Cipiti

June 2013 By Polly Clayden The last Pipeline Report described a bumper year for pediatric antiretroviral approvals. This one reports after a year in which new approvals were fewer and far between. Although the pipeline for children continues to look…

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The Antiretroviral Pipeline

  • Chad Cipiti

June 2013 By Simon Collins and Tim Horn NOTE: a postscript section at the end of this article includes periodic updates since publication in June 2013. Introduction The model of pricing newly approved antiretrovirals (ARVs) higher than current drugs is…

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Seven Ways to Speed Up the Pipeline

  • Chad Cipiti

June 2013 By Polly Clayden and Mark Harrington This chapter will discuss how to get the best drugs to the most people as quickly as possible; this requires that the compounds and combination products be: Discovered and developed in a…

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Dedication

  • Chad Cipiti

This report is dedicated to Spencer Cox March 10, 1968–December 18, 2012 Walter Kurtz Photography © 2006 Remarks on the Naming of the Spencer Cox Center for Health Melanie Thompson, MD New York City, June 11, 2013 I am so…

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