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Preventive Technologies: Antiretroviral and Vaccine Development

  • Chad Cipiti

July 2014 By Tim Horn and Richard Jefferys The U.S. Food and Drug Administration (FDA) approval of co-formulated tenofovir DF and emtricitabine (Truvada) as preexposure prophylaxis (PrEP) has transformed the HIV prevention landscape, though perhaps more in theory than reality.…

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Introduction and Executive Summary

  • Chad Cipiti

July 2014 By Polly Clayden and Mark Harrington INTRODUCTION Last year we wrote: [Getting] the best drugs to the most people as quickly as possible… requires that the compounds and combination products be: Discovered and developed in a high-quality research…

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The Antiretroviral Pipeline

  • Chad Cipiti

July 2014 By Tim Horn and Simon Collins Introduction By 2024, antiretroviral treatment (ART) could be as different from that used today as triple therapy in 1997 was from AZT monotherapy in 1987, or as dramatically evolved as the once-daily…

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Dedication

  • Chad Cipiti

July 2014 This report is dedicated to Marvin Oscar Shulman May 17, 1932–January 15, 2014 Marvin pictured, seated, second from left. A fierce AIDS warrior, principled leader, and beloved friend, Marvin Shulman was an activist’s activist. He dedicated himself completely…

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The Tuberculosis Diagnostics Pipeline

  • Chad Cipiti

July 2015 By Mark Harrington That things just go on like this is the catastrophe. —Walter Benjamin1 Introduction Because of the lack of effective, accessible point-of-care (POC) tests for all forms of tuberculosis (TB), 1.5 million people die of this…

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Momentum in the Pediatric Tuberculosis Treatment Pipeline

  • Chad Cipiti

July 2015 By Lindsay McKenna Introduction Years of building advocacy and research capacity have finally brought about clinical research for children with tuberculosis (TB). While data gaps and delays between adult and pediatric approvals remain large, there is more activity…

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Research Toward a Cure and Immune-Based and Gene Therapies

  • Chad Cipiti

July 2015 By Richard Jefferys Introduction The rise to prominence of cure research has continued over the past year, with every major scientific conference on HIV now featuring sessions and presentations on the topic. The U.S. National Institute of Allergy…

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