Clinical Trials Archives – Treatment Action Group

Research Toward a Cure Trials

August 15, 2022
Dorrit Walsh

A listing of clinical trials and observational studies related to the research effort to cure HIV infection, mainly derived from the clinicaltrials.gov online registry. Click the trial registry identifier numbers for a link to the full entry containing detailed information on the trial design, enrollment criteria, principal investigators and location(s).

Story: HIV Short Film, “Right To Try”

December 8, 2021
Dorrit Walsh

December 2021 Update, June 2022: The purported researcher responsible for the experiment described in this film, Serhat Gumrukcu, was indicted for murder-for-hire at the end of May 2022. The case is ongoing. In parallel, two independent investigations by financial media…

Story: The Esperanza Patient – Argentinian Woman’s Immune System May Have Cleared All Intact HIV

November 17, 2021
Dorrit Walsh

November 2021 Examples of media coverage: Woman’s own immune system has possibly cured her of HIV - Benjamin Ryan, NBC News, November 15, 2021 Scientists report finding a second person to be ‘naturally’ cured of HIV, raising hopes for future…

Story: Live Attenuated SHIV Vaccine Associated with Virus Clearance in Macaques

November 15, 2021
Dorrit Walsh

November 2021 Examples of media coverage: Research team develops vaccine that kills HIV in monkeys - The Asahi Shimbun, November 9, 2021 A New Vaccine Kills HIV in Monkeys. And It's Coming to Humans in 5 Years - Interesting Engineering,…

Unique Barriers to COVID-19 Vaccine Access for Black Communities

May 11, 2021
Dorrit Walsh

On Wednesday, May 19, 2021,Treatment Action Group (TAG), Black AIDS Institute, (BAI), and the COVID Prevention Trials Network (CoVPN) will convene a virtual news conference and roundtable discussion to disseminate findings from a soon-to-be published report: Breaking Barriers: Surveying Community Perspectives on COVID-19 Vaccine Research.

A Landscape Analysis of HIV Cure-Related Clinical Research in 2019

October 1, 2020
Dorrit Walsh

In 2018, the Bill & Melinda Gates Foundation contracted TAG to undertake a survey of investigators conducting studies included in our “Research Toward a Cure” clinical trials listing. TAG conducted this second survey in the fall of 2019 to track any changes over time and provide updated information on status of the field.

Statement on Human Challenge Studies for COVID-19 Vaccine Development

July 17, 2020
Dorrit Walsh

Two recent developments have brought renewed publicity to proposals to conduct human challenge studies to test COVID-19 vaccine candidates: an open letter from the organization 1DaySooner and media reports that Adrian Hill’s Oxford University research group is planning a challenge study, taking advantage of the lack of regulatory oversight of human challenge experiments in the United Kingdom.

Treatment Action Group Statement on New HIV Remission Case Report at AIDS2020

July 8, 2020
Dorrit Walsh

Yesterday, a widely reported presentation by Ricardo Diaz at the ongoing virtual International AIDS Conference (AIDS2020) disclosed that one out of 30 total participants in an HIV cure-related research trial conducted in Brazil has not experienced an HIV viral load rebound for a little over a year (64.7 weeks) after interrupting antiretroviral therapy (ART).

AVAC and TAG Statement on Ethical Conduct of SARS-CoV-2 Vaccine Challenge Studies

May 7, 2020
Dorrit Walsh

The COVID-19 pandemic is a global health emergency that may demand new, safe, and expedited ways of conducting ethical research to find the solutions we need, including a safe and effective vaccine.

Treatment Action Group and the PrEP4All Collaboration Respond to Reported Remdesivir Results for COVID-19

April 30, 2020
Dorrit Walsh

Treatment Action Group (TAG) and the PrEP4All Collaboration welcome results from randomized controlled trials of therapies for COVID-19, but are seriously concerned about claims that data from a National Institutes of Allergy and Infectious Diseases (NIAID) study of the Gilead drug remdesivir...