Clinical Trials Archives – Treatment Action Group

Response to Tuberculosis Treatment Trials Results Published and Presented During the 2022 Union World Conference on Lung Health

November 16, 2022
Dorrit Walsh

Treatment Action Group (TAG) and the Global Tuberculosis Community Advisory Board (TB CAB) welcome the clinical trials results recently published and presented during the 2022 Union World Conference on Lung Health, which evaluated shorter regimens and treatment shortening strategies for drug-sensitive and drug-resistant tuberculosis.

Research Toward a Cure Trials

November 16, 2022
Dorrit Walsh

A listing of clinical trials and observational studies related to the research effort to cure HIV infection, mainly derived from the clinicaltrials.gov online registry. Click the trial registry identifier numbers for a link to the full entry containing detailed information on the trial design, enrollment criteria, principal investigators and location(s).

Treatment Action Group Resource on the Demographics of Participation in HIV Cure-Related Clinical Research

October 20, 2022
Dorrit Walsh

In 2014, TAG began tracking HIV cure-related trials and observational studies and making the information available as a listing on our website. The primary sources are online study registries, particularly the US-based clinicaltrials.gov.

Pathways Forward to End HIV: How HIV Cure Research is Helping to Advance HIV Vaccine Research

August 24, 2022
Dorrit Walsh

On September 20, please join Treatment Action Group, Dr. Shelly Karuna, and Dr. Karine Dubé for a webinar on the next generation of bnAbs trial design and ethics related to ATIs in HIV vaccine and cure research.

Story: HIV Short Film, “Right To Try”

December 8, 2021
Dorrit Walsh

December 2021 Update, June 2022: The purported researcher responsible for the experiment described in this film, Serhat Gumrukcu, was indicted for murder-for-hire at the end of May 2022. The case is ongoing. In parallel, two independent investigations by financial media…

Story: The Esperanza Patient – Argentinian Woman’s Immune System May Have Cleared All Intact HIV

November 17, 2021
Dorrit Walsh

November 2021 Examples of media coverage: Woman’s own immune system has possibly cured her of HIV - Benjamin Ryan, NBC News, November 15, 2021 Scientists report finding a second person to be ‘naturally’ cured of HIV, raising hopes for future…

Story: Live Attenuated SHIV Vaccine Associated with Virus Clearance in Macaques

November 15, 2021
Dorrit Walsh

November 2021 Examples of media coverage: Research team develops vaccine that kills HIV in monkeys - The Asahi Shimbun, November 9, 2021 A New Vaccine Kills HIV in Monkeys. And It's Coming to Humans in 5 Years - Interesting Engineering,…

Unique Barriers to COVID-19 Vaccine Access for Black Communities

May 11, 2021
Dorrit Walsh

On Wednesday, May 19, 2021,Treatment Action Group (TAG), Black AIDS Institute, (BAI), and the COVID Prevention Trials Network (CoVPN) will convene a virtual news conference and roundtable discussion to disseminate findings from a soon-to-be published report: Breaking Barriers: Surveying Community Perspectives on COVID-19 Vaccine Research.

A Landscape Analysis of HIV Cure-Related Clinical Research in 2019

October 1, 2020
Dorrit Walsh

In 2018, the Bill & Melinda Gates Foundation contracted TAG to undertake a survey of investigators conducting studies included in our “Research Toward a Cure” clinical trials listing. TAG conducted this second survey in the fall of 2019 to track any changes over time and provide updated information on status of the field.

Statement on Human Challenge Studies for COVID-19 Vaccine Development

July 17, 2020
Dorrit Walsh

Two recent developments have brought renewed publicity to proposals to conduct human challenge studies to test COVID-19 vaccine candidates: an open letter from the organization 1DaySooner and media reports that Adrian Hill’s Oxford University research group is planning a challenge study, taking advantage of the lack of regulatory oversight of human challenge experiments in the United Kingdom.