An overview of current knowledge regarding how HIV persists in the body despite suppression of viral load by antiretroviral therapy. Understanding the mechanisms by which HIV persists is considered key to developing curative interventions that would prevent the virus rebounding when antiretroviral therapy is stopped.
HIV Persistence Module (PowerPoint)
HIV Persistence Module (PDF)
Additional Resources
Supporting Videos:
- HIV Reservoirs: Lessons for Cure by Daniel Douek, IAS 2021
Background References:
- C Cohn LB, Chomont N, Deeks SG. The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies. Cell Host Microbe. 2020;27(4):519-530.