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Amino acid substitutions conferring reduced sensitivity to selected protease inhibitors:

saquinavir (Invirase) 10 48 54 63
ritonavir (Norvir) 20 36 46 54 63 71 82 84 90
indinavir (Crixivan) 10 20 24 36 46 54 63 64 71 82 84 90 193
nelfinavir (Viracept) 30 36 46 63 77 88 90
141W94 (aka VX478) 10 46 47 50 84

 

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