An overview of current knowledge regarding how HIV persists in the body despite suppression of viral load by antiretroviral therapy. Understanding the mechanisms by which HIV persists is considered key to developing curative interventions that would prevent the virus rebounding…
Scientists are pursuing multiple approaches with the aim of developing interventions capable of curing HIV or keeping HIV durably suppressed in the absence of antiretroviral therapy. This module provides an overview of the many strategies that are currently under investigation…
Ethics are a cornerstone of all scientific research, providing principles by which studies should be conducted to ensure that participants are properly informed and that any risks are justified and acceptable. This module provides background on research ethics and covers…
An introductory overview of the research effort to develop a cure for HIV infection. Topics covered include terms and definitions used in HIV cure research, the reasons why a cure is needed, evidence supporting that a cure is possible, and…
Treatment Action Group (TAG) welcomes and celebrates the U.S. Food and Drug Administration’s (FDA) approval of Apretude brand cabotegravir, the first injectable medication for use as pre-exposure prophylaxis (PrEP) to reduce the risk of HIV transmission.
As we look forward to an end of an extremely challenging year—and past four years—we reflect on the remarkable resilience and impact of TAG, even and especially in these dark times.
December 2021 Update, October 2025: On September 30, 2025, the US Department of Justice announced that Serhat Gumrukcu was convicted by a jury on April 18, 2025 for his role in the murder for hire conspiracy. Update, June 2022: The…
November 2021 Examples of media coverage: Scientists report finding a second person to be ‘naturally’ cured of HIV, raising hopes for future treatments - Megan Molteni, STAT News, November 15, 2021 A Second Woman May Be Naturally Cured of HIV…
November 2021 Examples of media coverage: Research team develops vaccine that kills HIV in monkeys - The Asahi Shimbun, November 9, 2021 A New Vaccine Kills HIV in Monkeys. And It's Coming to Humans in 5 Years - Interesting Engineering,…
Developing an HIV vaccine is a difficult scientific challenge, but remains a critical priority. This handout provides an update on HIV vaccine research and a summary of results from the efficacy trials that have been conducted to date, and it…
Read an hour-by-hour breakdown of how our HIV team works at the forefront of research, education, and advocacy, and donate today.
