Research Toward a Cure Trials
A listing of clinical trials and observational studies related to the research effort to cure HIV infection, mainly derived from the clinicaltrials.gov online registry.
Story: HIV cure “breakthrough” with mRNA-delivered Tat protein
June 2025 Media coverage: Breakthrough in search for HIV cure leaves researchers ‘overwhelmed’ - Kat Lay, The Guardian, June 5, 2025 Major breakthrough in battle for HIV cure ‘previously thought impossible’ - Athena Stavrou, Independent, June 5, 2025 Used in…
2025 Pre-CROI Community HIV Cure Research Workshop
The 2025 Pre-CROI Community HIV Cure Research Workshop will take place on Saturday, March 8 in San Francisco.
Story: HIV “completely eliminated” from cells in a laboratory dish with CRISPR technology
March 2024 Media coverage: Scientists say they can cut HIV out of cells - Michelle Roberts, BBC, March 20, 2024 HIV cure breakthrough as virus eliminated from cells in laboratory - Nina Massey, The Independent, March 20, 2024 Hopes of…
2024 Pre-CROI Community HIV Cure Research Workshop
The 2024 Pre-CROI Community HIV Cure Research Workshop took place on Saturday, March 2nd in Denver. This year’s workshop had a shorter format than in the past, but we plan to return to an all-day event in the future.
A Community Update on AbbVie’s HIV Cure Research Program
This webinar was held on December 5, 2023, and provided an update on HIV cure-related research studies being conducted by the company AbbVie; the recording of the webinar is now online.
Story: CRISPR-Based Cure for HIV “could be months away”
October/November 2023 Media coverage: CRISPR gene therapy appears safe, but claims of an imminent HIV cure are premature - Liz Highleyman, AIDSMap, November 3, 2023 Cure for HIV could be months away as first three patients are injected with new…
Pathways Forward to End HIV: How HIV Cure Research is Helping to Advance HIV Vaccine Research
On September 20, please join Treatment Action Group, Dr. Shelly Karuna, and Dr. Karine Dubé for a webinar on the next generation of bnAbs trial design and ethics related to ATIs in HIV vaccine and cure research.
CUREiculum 2.0: Community & Stakeholder Engagement in HIV Cure-Related Research Module
Engagement of affected communities in research is vital to ensuring that the science is ethical and responsive to community priorities and needs. This module covers the history of community-based HIV research advocacy and outlines principles and best practices for community…
CUREiculum 2.0: Analytical Treatment Interruptions (ATI) Module
Some HIV cure research studies ask participants to temporarily stop antiretroviral therapy, which is referred to as an analytical treatment interruption (ATI). This module explains the use of ATIs in HIV cure research and covers what is currently known about…